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作者：James D. McGettrick;Wayne C. E. Schofield;Richard P. Garrod;Jas Pal S. Badyal;

作者單位：Chemistry Department, Science Laboratories, Durham University Durham DH1 3LE, England (UK);Chemistry Department, Science Laboratories, Durham University Durham DH1 3LE, England (UK);Chemistry Department, Science Laboratories, Durham University Durham DH1

刊名：Chemical vapor deposition

ISSN：0948-1907

出版年：2009-01-05

卷：15

期：41005

起頁：122

止頁：127

分類號：TQ175

語種：英文

關(guān)鍵詞：Surface functionalization;Bioarrays;DNA;Oligonucleotides;

內(nèi)容簡介

A highly efficient approach for the covalent immobilization of single-strand DNA onto solid surfaces and their subsequent hybridization to complementary strands is described. This entails pulsed plasma deposition of poly(3-vinylbenzaldehyde) followed by the Schiff-base reaction. A range of substrates, including glass slides, silicon wafers, polystyrene microspheres, and single-walled carbon nanotubes (SWNTs), are functionalized employing this methodology.